Medical School

Sep 20

The Human Heart
Volume Rendering of a contrast enhanced cardiac CT

The Human Heart

Volume Rendering of a contrast enhanced cardiac CT

(Source: farm7.staticflickr.com)

Sep 19

Pancreatic Cancer
Palladin Expression in Primary Cultures of Pancreatic Ductal Cells Derived from Increasingly Neoplastic Samples. Expression of Palladin RNA increases relative to the degree of precancer to cancer: normal to PanIN 1 (hyperplasia) to PanIN 3 (carcinoma in situ) to cancer. Each bar represents epithelial cell cultures from one person. The PanIN 1 and PanIN 3 lesions (lower left photomicrograph) were purified from two affected members of Family X. The pancreatic cancer epithelial cells (lower right photomicrograph) were purified from a sample of sporadic adenocarcinoma.

Pancreatic Cancer

Palladin Expression in Primary Cultures of Pancreatic Ductal Cells Derived from Increasingly Neoplastic Samples. Expression of Palladin RNA increases relative to the degree of precancer to cancer: normal to PanIN 1 (hyperplasia) to PanIN 3 (carcinoma in situ) to cancer. Each bar represents epithelial cell cultures from one person. The PanIN 1 and PanIN 3 lesions (lower left photomicrograph) were purified from two affected members of Family X. The pancreatic cancer epithelial cells (lower right photomicrograph) were purified from a sample of sporadic adenocarcinoma.

Sep 17

White matter is one of the two components of the central nervous system and consists mostly of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid tissue veined with capillaries. Its white color is due to its usual preservation in formaldehyde.
White matter is composed of bundles of myelinated nerve cell processes (or axons), which connect various grey matter areas (the locations of nerve cell bodies) of the brain to each other, and carry nerve impulses between neurons. Myelin acts as an insulator, increasing the speed of transmission of all nerve signals.
Image: White matter structure of human brain (taken by MRI).

White matter is one of the two components of the central nervous system and consists mostly of glial cells and myelinated axons that transmit signals from one region of the cerebrum to another and between the cerebrum and lower brain centers. White matter tissue of the freshly cut brain appears pinkish white to the naked eye because myelin is composed largely of lipid tissue veined with capillaries. Its white color is due to its usual preservation in formaldehyde.

White matter is composed of bundles of myelinated nerve cell processes (or axons), which connect various grey matter areas (the locations of nerve cell bodies) of the brain to each other, and carry nerve impulses between neurons. Myelin acts as an insulator, increasing the speed of transmission of all nerve signals.

Image: White matter structure of human brain (taken by MRI).

(Source: Wikipedia)

Sep 16

Two cell blastomere (1-2 days post-fertilization)

Two cell blastomere (1-2 days post-fertilization)

(Source: php.med.unsw.edu.au)

Sep 15

[video]

Sep 14

“All bleeding eventually stops.” — Jeffrey M. Goller M.D.

Sep 13

ATP production in mitochondria (purple) can lead to the formation of reactive oxygen species (ROS) that damage mitochondria. When an organelle is beyond repair, the cellular recycling system (green) kicks-in and targets them for mitophagy, a specialized form of mitochondrial degradation.
Image: A primary retinal ganglion cell expresses a red fluorescent protein targeted to mitochondria, a green fluorescent protein fused to the autophagosomal marker LC3, and a cyan fluorescent protein in the cytosol. This image reveals how autophagosomes (green) can contact individual mitochondria (purple), before their ingestion by mitophagy.

ATP production in mitochondria (purple) can lead to the formation of reactive oxygen species (ROS) that damage mitochondria. When an organelle is beyond repair, the cellular recycling system (green) kicks-in and targets them for mitophagy, a specialized form of mitochondrial degradation.

Image: A primary retinal ganglion cell expresses a red fluorescent protein targeted to mitochondria, a green fluorescent protein fused to the autophagosomal marker LC3, and a cyan fluorescent protein in the cytosol. This image reveals how autophagosomes (green) can contact individual mitochondria (purple), before their ingestion by mitophagy.

(Source: download.cell.com)

Sep 12

Micrograph of non-alcoholic fatty liver disease, demonstrating marked macrovesicular steatosis.

Micrograph of non-alcoholic fatty liver disease, demonstrating marked macrovesicular steatosis.

(Source: Wikipedia)

Sep 11

Early Heart Tube (Lateral View)
Angiogenesis throughout the embryo allows for the development of angioblastic cords in the cardiogenic mesoderm of the embryo.

Early Heart Tube (Lateral View)

Angiogenesis throughout the embryo allows for the development of angioblastic cords in the cardiogenic mesoderm of the embryo.

(Source: php.med.unsw.edu.au)

Sep 10

forbes:

Can the world’s richest doctor fix healthcare? 

forbes:

Can the world’s richest doctor fix healthcare? 

Electrocardiogram of a patient with pulmonary embolism showing sinus tachycardia of approximately 150 beats per minute and right bundle branch block.

Electrocardiogram of a patient with pulmonary embolism showing sinus tachycardia of approximately 150 beats per minute and right bundle branch block.

(Source: Wikipedia)

Sep 09

[video]

Sep 08

The Neural Tube
 the neural tube forms the brain and spinal cord
fusion of neural groove extends rostrally and caudally
begins at the level of 4th somite
closes neural groove “zips up” in some species.
humans appear to close at multiple points along the tube.

leaves 2 openings at either end - Neuropores
cranial neuropore closes before caudal

Failure for the neural tube to close correctly or completely results in a neural tube defect. 

The Neural Tube

Failure for the neural tube to close correctly or completely results in a neural tube defect

(Source: php.med.unsw.edu.au)

Sep 07

[video]

Sep 06

Gross pathology of rheumatic heart disease: aortic stenosis. Aorta has been removed to show thickened, fused aortic valve leaflets and opened coronary arteries from above.

Gross pathology of rheumatic heart disease: aortic stenosis. Aorta has been removed to show thickened, fused aortic valve leaflets and opened coronary arteries from above.