H1N1 Virus
(Source: dailycontributor.com)
Adventures in Medical School
Influenza A strains that can infect mammals (eg, pigs and humans) may undergo genetic reassortment through contact with avian strains. The reassortment of an avian strain with a mammalian strain may produce a chimeric virus that is transmissible between mammals; such mutation products may contain hemagglutinin and/or neuraminidase proteins that are unrecognizable to the immune systems of mammals. This antigenic shift results in a much greater population of susceptible individuals in whom more severe disease is possible.
Influenza
In the current outbreak in the United States, preliminary testing has shown the same genetic pattern in all cases of the virus. The virus is being described as a new subtype of influenza A/H1N1, one that has not previously been detected in either swine or humans. On April 26, 2009, the US Department of Health and Human Services declared a national public health emergency involving swine influenza A, citing its significant potential to affect national security.
Influenza